pentobarbital will minimize the level or result of armodafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.pentobarbital will reduce the level or influence of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of abemaciclib with potent CY